Potential of advanced MR imaging techniques in the differential diagnosis of parkinsonism
Identifieur interne : 002128 ( Main/Exploration ); précédent : 002127; suivant : 002129Potential of advanced MR imaging techniques in the differential diagnosis of parkinsonism
Auteurs : Anna Hotter [Autriche] ; Regina Esterhammer [Autriche] ; Michael F. H. Schocke [Autriche] ; Klaus Seppi [Autriche]Source :
- Movement Disorders [ 0885-3185 ] ; 2009.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Atrophy, Brain (pathology), DWI, Diagnosis, Differential, Differential diagnostic, Diffusion Magnetic Resonance Imaging, Humans, Image Processing, Computer-Assisted, MR, Magnetic Resonance Imaging (methods), Nervous system diseases, Nuclear magnetic resonance imaging, Parkinson Disease (diagnosis), Parkinson Disease (pathology), Parkinsonism, Protons, Technique, differential diagnosis, parkinsonism.
- MESH :
- chemical : Protons.
- diagnosis : Parkinson Disease.
- methods : Magnetic Resonance Imaging.
- pathology : Brain, Parkinson Disease.
- Atrophy, Diagnosis, Differential, Diffusion Magnetic Resonance Imaging, Humans, Image Processing, Computer-Assisted.
Abstract
The clinical differentiation of parkinsonian syndromes remains challenging not only for neurologists but also for movement disorder specialists. Conventional magnetic resonance imaging (cMRI) with the visual assessment of T2‐ and T1‐weighted imaging as well as different advanced MRI techniques offer objective measures, which may be a useful tool in the diagnostic work‐up of Parkinson's disease and atypical parkinsonian disorders (APDs). In clinical practice, cMRI is a well‐established method for the exclusion of symptomatic parkinsonism due to other pathologies. Over the past two decades, abnormalities in the basal ganglia and infratentorial structures have been shown especially in APDs not only by cMRI but also by different advanced MRI techniques, including methods to assess regional cerebral atrophy quantitatively such as magnetic resonance volumetry, proton magnetic resonance spectroscopy, diffusion‐weighted imaging, and magnetization transfer imaging. This article aims to review recent research findings on the role of advanced MRI techniques in the differential diagnosis of neurodegenerative parkinsonian disorders. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22648
Affiliations:
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<front><div type="abstract" xml:lang="en">The clinical differentiation of parkinsonian syndromes remains challenging not only for neurologists but also for movement disorder specialists. Conventional magnetic resonance imaging (cMRI) with the visual assessment of T2‐ and T1‐weighted imaging as well as different advanced MRI techniques offer objective measures, which may be a useful tool in the diagnostic work‐up of Parkinson's disease and atypical parkinsonian disorders (APDs). In clinical practice, cMRI is a well‐established method for the exclusion of symptomatic parkinsonism due to other pathologies. Over the past two decades, abnormalities in the basal ganglia and infratentorial structures have been shown especially in APDs not only by cMRI but also by different advanced MRI techniques, including methods to assess regional cerebral atrophy quantitatively such as magnetic resonance volumetry, proton magnetic resonance spectroscopy, diffusion‐weighted imaging, and magnetization transfer imaging. This article aims to review recent research findings on the role of advanced MRI techniques in the differential diagnosis of neurodegenerative parkinsonian disorders. © 2009 Movement Disorder Society</div>
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